Rubber comes from the latex (sap) of a large tree (Hevea brasiliensis). Its first use was for erasers, for rubbing out pencil marks. Invention of the pneumatic tire such as on cars and bicycles led to its being essential to industrial economies. This product was of major importance to the industrial revolution and played a central role in the early commercialization of the Amazon region. It remained an essential international commodity until the development of synthetic alternatives. The one inch long seeds are commonly used in handicrafts, such as necklaces.